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PHARMACEUTICAL PACKAGING BY METALS
PRESENTED BY : SHAGUFTA KHAN B. PHARM VIII SEMESTER
PHARMACEUTICAL PACKAGING Pharmaceutical packaging is the means of providing protection,
presentation, identification and information, containment, convenience to encourage compliance with and closures.
and
FDA-
Packaging is the science, art and technology of enclosing or protecting products for distribution, storage, sale, and use. An economical means of providing protection, presentation,
identification, information and convenience for pharmaceuticals product from the moment of production until it is used or administered.
METALS Metals used in packaging including Tin (15%) Aluminum (60%) Lead (25%)
These metals are useful in the preparation of collapsible tubes. Type of metal containers
a. Collapsible tubes b. Metal containers for tablets and capsules c. Metal foil
TIN Tin: F00D PHARMACEUTICA LS product for which purity is an important consideration
ADVANTAGES • Tin is chemically inert of all collapsible tube metals. • It offers a good appearance and compatibility with a wide
range of products.
Aluminum
Aluminum tubes offer significant savings in
product shipping costs because of their light weight. They provide good appearance
Lead Lead has the lowest cost of all tube metals and is
widely used for nonfood products such as adhesives, inks, paints, and lubricants. Lead should never be used alone for anything
taken internally because of the risk of lead poisoning. The inner surface of the lead tubes are coated
and are used for products like fluoride toothpaste.
Type of metal containers: Collapsible tubes Metal containers for tablets and capsules Metal foil
COLLAPSIBLE TUBES The collapsible metal tube is an attractive
container that permits controlled amounts to be dispensed easily, with good re closure and adequate environmental protection to the product. The risk of contamination of the portion remaining in the tube is minimal, because the tube does not "suck back.“ It is light in weight and unbreakable, and it lends itself to high-speed automatic filling operations. The ductile metals used for collapsible tubes are tin (15%), aluminum (60%), and lead (25%)
COLLAPSIBLE TUBES Collapsible Tubes
Plastic Collapsible Tubes
Laminated tubes Metal Collapsible Tubes
METAL COLLAPSIBLE TUBES
Advantages Permits controlled amount to be dispensed easily with good reclosuer & provides adequate protection to the product.
Does not suck back Disadvantages Corrosion & Breakage
METAL FOILS Thin sheets of metals. <100 µm thickness. Aluminium barrier Attractive Reflective surface Thick alluminium sheets – tray for blister pack. Thin alluminium foil – vaccum depositioning.
Metal foils
Containers for tablet and capsules
Closures Emphasised On Metals Closures-
METALS 1.Tin 2. Aluminium Closures Are Available In 5 Basic Designs 1) Screw-on Closure 2) Crimp-on Closure 3) Roll-on Closure 4) Friction Closure 5) Press-on Closure
SCREW CAP CLOSURES
ROLL ON
Tamper Resistant Packaging As per FDA It is a packaging in which there is an indication or barrier to entry which if breached or missing, can reasonably be expected to provide visible evidence to consumer that tampering has occurred.
Tamper Resistant Packaging o o o o o o o o
o o
Film wrappers Blister package Strip package Bubble pack Shrink seal & bands Aerosol containers Bottle seals Tape seals Breakable caps Foil, paper or plastic pouch
FILM WRAPPERS
BLISTER PACKAGING
STRIP PACKING
AEROSOL CONTAINERS
Advantage of Metals They are sturdy.
They are impermeable to light, moisture,and
gas. They are light in weight as compared to glass containers. Labels can be printed directly on to their surface.
Disadvantage of metals They are expensive.
They may shed metal particles into
pharmaceutical products. They are not generally used for extemporaneous dispensing. They react with certain chemicals of drug.
THANK YOU….