Osteoarthritis Concept Map
This document was uploaded by user and they confirmed that they have the permission to share it. If you are author or own the copyright of this book, please report to us by using this DMCA report form. Report DMCA
Overview
Download & View Osteoarthritis Concept Map as PDF for free.
More details
- Words: 122
- Pages: 1
Loading documents preview...
Risk Factors
Envionmental & Behavioral
Age & Sex
Genetics Congenital Abnormalities
Obesity Occupational Repetitive Motion
Cytokine – interleukin promotes synthesis of MMPs & suppresses synthesis of collagen & proteoglycans
Hormone Disorders
Repeated Trauma
Physiological Changes
OSTEOARTHRITIS
of matrix degrading enzymes - metalloproteinases (MMPs)
Collagen in
Proteoglycans
matrix
in matrix
Gout
chondrocytes
Diabetes
proteoglycans collagen molecules Overwhelming of matrix degrading enzymes - metalloproteinases Fibrillation of cartilage Lifestyle changes
Crepitus Stress fractures
Inflammation
Erosion of cartilage Cracking of cartilage
Localized inflammation Chronic inflammation
Cartilage matrix degradation
Joint swelling Chronic gout Joint tenderness
Observable erosions to articular cartilage
Difficulty walking Joint stiffness
Range of motion Joint pain
Manifestations
Osteoarthritis Difficulty climbing stairs Osteonecrosis
Complications
Ashley Dean RNSG1263
Envionmental & Behavioral
Age & Sex
Genetics Congenital Abnormalities
Obesity Occupational Repetitive Motion
Cytokine – interleukin promotes synthesis of MMPs & suppresses synthesis of collagen & proteoglycans
Hormone Disorders
Repeated Trauma
Physiological Changes
OSTEOARTHRITIS
of matrix degrading enzymes - metalloproteinases (MMPs)
Collagen in
Proteoglycans
matrix
in matrix
Gout
chondrocytes
Diabetes
proteoglycans collagen molecules Overwhelming of matrix degrading enzymes - metalloproteinases Fibrillation of cartilage Lifestyle changes
Crepitus Stress fractures
Inflammation
Erosion of cartilage Cracking of cartilage
Localized inflammation Chronic inflammation
Cartilage matrix degradation
Joint swelling Chronic gout Joint tenderness
Observable erosions to articular cartilage
Difficulty walking Joint stiffness
Range of motion Joint pain
Manifestations
Osteoarthritis Difficulty climbing stairs Osteonecrosis
Complications
Ashley Dean RNSG1263
Related Documents
Osteoarthritis Concept Map
February 2021 0
Concept Map
February 2021 1
Concept Map Of Globalization
February 2021 1
Concept Map Sts
March 2021 0
Cell Membrane Concept Map
February 2021 0
Concept Map Of.docx
February 2021 0More Documents from "belgacac3967"