Patofisiologi Osteoarthritis
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Patofisiologi Osteoarthritis Padrepio Ragil Rahadi 1010108
Degradasi kolagen matriks kartilago ↑
Inflamasi, mediator: interleukin
hang at ROM terbat as
Obesitasbeban sendi bertambah
Permukaan tulang kasar
Cuaca dingin Vasokontriksi pembuluh darah
nyeri bengka k
Remodelling+hi pertrofi tulang
Menekan ujung syaraf di periosteum Iritasi membran synovial
proteoglikan↓,a ir↑
osteofit Terleaps ke ruang synovial
Synovitisakum ulasi cariran eksudat inflamasi ke cavitas artikularis
Genu varu m Gesekan antar tulang meningka t
crepitu s
Tulang abrasi (eburnation) Tumbuh kartilago+tulang di tepi sendi
Degradasi kolagen matriks kartilago ↑
Inflamasi, mediator: interleukin
hang at ROM terbat as
Obesitasbeban sendi bertambah
Permukaan tulang kasar
Cuaca dingin Vasokontriksi pembuluh darah
nyeri bengka k
Remodelling+hi pertrofi tulang
Menekan ujung syaraf di periosteum Iritasi membran synovial
proteoglikan↓,a ir↑
osteofit Terleaps ke ruang synovial
Synovitisakum ulasi cariran eksudat inflamasi ke cavitas artikularis
Genu varu m Gesekan antar tulang meningka t
crepitu s
Tulang abrasi (eburnation) Tumbuh kartilago+tulang di tepi sendi
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